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All Journal Jurnal Kesehatan Masyarakat Nexus Kedokteran Klinik Sari Pediatri Paediatrica Indonesiana Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Health Promotion and Behavior Journal of Maternal and Child Health Amerta Nutrition
Harsono Salimo
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Journal : Nexus Kedokteran Klinik

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Hubungan antara Kadar Feritin dengan Kreatinin Serum pada Pasien Thalassemia di RSUD Dr. Moewardi Utami, Eko Dewi Ratna; Salimo, Harsono; Budiani, Dyah Ratna
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Patients with thalassemia that underwent routine blood transfusion are developing iron overload. In the state of excess iron, ferritin levels increase. When iron storage capacity has been depleted, free iron will cause tissue damage. One of that damaged organ is kidney. One of parameter used to know the function of kidney is GFR (Glomerular Filtration Rate). A simple way to estimate GFR is serum creatinine. Increased 1-2 mg/dL of creatinine serum showed decrease ±50% of GFR. This research was aimed to determine the correlation between ferritin levels and serum creatinine of patients with thalassemia. Methods : A cross-sectional study which the subjects were 30 patients with thalassemia in the pediatric ward RSUD Dr. Moewardi who met the inclusion criteria. Ferritin levels and serum creatinine obtained from medical records or patient report book. Data normality was tested with Shapiro-Wilk normality test. Correlation between ferritin levels and serum creatinine were analyzed with non-parametric correlation test Spearman using Statistical Product and Service Solutions (SPSS) 20.0 for Windows. Results : Ferritin levels ranged from 1004.2 to 9600 ng/mL. Creatinine serum were 0.2 mg/dL; 0.3 mg/dL; 0.4 mg/dL; 0.5 mg/dL with almost equal distribution. Results of the analysis with non-parametric correlation test Spearman obtained R = 0.044 and p = 0.816. Conclusion : There was no correlation between ferritin levels and serum creatinine of patients with thalassemia. Keywords : thalassemia, ferritin, creatinine
Hubungan antara Kadar Feritin dengan Kreatinin Serum pada Pasien Thalassemia di RSUD Dr. Moewardi Eko Dewi Ratna Utami; Harsono Salimo; Dyah Ratna Budiani
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background : Patients with thalassemia that underwent routine blood transfusion are developing iron overload. In the state of excess iron, ferritin levels increase. When iron storage capacity has been depleted, free iron will cause tissue damage. One of that damaged organ is kidney. One of parameter used to know the function of kidney is GFR (Glomerular Filtration Rate). A simple way to estimate GFR is serum creatinine. Increased 1-2 mg/dL of creatinine serum showed decrease 50% of GFR. This research was aimed to determine the correlation between ferritin levels and serum creatinine of patients with thalassemia. Methods : A cross-sectional study which the subjects were 30 patients with thalassemia in the pediatric ward RSUD Dr. Moewardi who met the inclusion criteria. Ferritin levels and serum creatinine obtained from medical records or patient report book. Data normality was tested with Shapiro-Wilk normality test. Correlation between ferritin levels and serum creatinine were analyzed with non-parametric correlation test Spearman using Statistical Product and Service Solutions (SPSS) 20.0 for Windows. Results : Ferritin levels ranged from 1004.2 to 9600 ng/mL. Creatinine serum were 0.2 mg/dL; 0.3 mg/dL; 0.4 mg/dL; 0.5 mg/dL with almost equal distribution. Results of the analysis with non-parametric correlation test Spearman obtained R = 0.044 and p = 0.816. Conclusion : There was no correlation between ferritin levels and serum creatinine of patients with thalassemia. Keywords : thalassemia, ferritin, creatinine
Co-Authors -, Suradi Abd. Rasyid Syamsuri Adi Magna Patriadi Nuhriawangsa Alfianrisa, Anggityas Alinda Nur Ramadhani Anggraini, Yeni Anindya, Ivanda Glanny Annang Giri Moelyo Annang Giri Moelyo Argyo Demartoto, Argyo Aries - Krisbiyantoro Astuti, Fitriyani Dwi Atika, Zummatul Ayuningrum, Ika Yuli Bachtiar, Harrys Bhisma Murti Burhannudin Ichsan Catur Retno Lestari Desi Ekawati Diana Mayasari Hadianto Didik Tamtomo, Didik Dwi Hidayah Dwi Wijayanti Dyah Ratna Budiani Eko Dewi Ratna Utami Endang Dewi Lestari Endang Sutisna Sulaeman Eti Poncorini Pamungkasari Fauziyah, Rahma Galih Herlambang H.A.A. Soebijanto Hardilla, Dinda Septiani Hartanti, Ainurrizma Tri Ilma, Nabilah Nurul Ilma, Nabilah Nurul Indita, Wiwen Indriasih, Merlita Indriasih, Merlita Indriyani, Eny Inggar Ratna Kusuma Irnawati, Prita Yuliana Iskandar, Nurdin Aji Ivanda Glanny Anindya Juhrotun Nisa, Juhrotun Khalifah, Intan Noor Khalifatunisak, Alfadefi Kusumastuti, Nurry Ayuningtyas Kusumawardhani, Wahyu Kuswandari, Eti Leilani Lestarina Lestari, Nining Lilisianawati Lilisianawati Listiani, Funik Rahma Mei Maria Galuh Kamenyangan Sari Marlinawati, Iin Tri MS, Novi Paramitasari Muslimah, Putri Andini Ningsih, Nur Isniani Nugraha, Sandi Nugroho, Irfan Dzakir Nurahmawati, Dhewi Nurmayanti, Rika Palupi, Endang Poncorini, Eti Rahardjo, Setyo Sri Rita Adriani Benya Adriani Riza, Muhamad Rohaniyati, Retno Dwi Rokhayati, Rokhayati Rokhayati, Rokhayati Safriana, Latifah Saptawati Bardosono Sari, Lutfiana Puspita Sinta, Prabawati Sri Lilijanti Widjaja Sukoco, Amin Susanti, Isne Titah Pujangkara, Ajeng Ayu Trisnawati, Iga Uki Retno Budihastuti Vitri Widyaningsih yulia lanti retno dewi Yulia Lanti Retno Dewi Yulidar Hafidh